19. Antioxidant activity of Japanese skin care product Runn-Runn
Osato J.A., Santiago L.A., and Mori A
Magnetic Resonance in Medicine. 6:324-326;1995

        Runn-Runn, a brown granular face wash and body skin care made by fermentation of rice bran, Bio-Normalizer and other plant extracts, has been found to scavenge hydroxyl, superoxide & carbon-centered radicals and DPPH. The activity may be ascribed to its two major antioxidative components, Bio-normzlier and rice bran. (Rice bran is rich with known antioxidants such as alpha-tocopherol, oryzanol, isovitexin, squalene, phenolic compounds, and superoxide dismutase-like activity).

       Cancer of the skin implicates free radicals generated by ultraviolet irradiation. These harmful species can cause accelerated aging, excessive oxidants, increased collagen synthesis and lipid peroxidation, thereby damaging the skin. As such, Runn-runn may be used as an antioxidant for skin dare treatment.